I’m just a frog married to a pommy, living in the land of roast beef following a few colourful stays across the continents (https://youtu.be/CfMDsyAW-Zg) . I’m also permanently puzzled by what life is all about thanks in part to our 3 hybrids, one with Down syndrome. It’s usually manic and chaotic but the rough edges usually get ironed out by our 4-legged addition. Denise Humberstone, trustee and editor-in-chief at Making Chromosomes Count magazine.